methyl 7-{(3R)-5-oxo-3-[(triethylsilyl)oxy]cyclopent-1-en-1-yl}heptanoate - Names and Identifiers
Name | methyl 7-{(3R)-5-oxo-3-[(triethylsilyl)oxy]cyclopent-1-en-1-yl}heptanoate
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Synonyms | (3R)-5-Oxo-3-[(triethylsilyl)oxy]- (3R)-5-Oxo-3-[(triethylsilyl)oxy]-1-cyclopentene-1-heptanoic methyl 8-(3-Triethyl silyloxy-5-oxocyclopent-1-enyl)octanoate. (R)-Methyl 7-(5-oxo-3-((triethylsilyl)-oxy)cyclopent-1-en-1-yl)heptanoate methyl 7-{(3R)-5-oxo-3-[(triethylsilyl)oxy]cyclopent-1-en-1-yl}heptanoate (3R)-5-Oxo-3-[(triethylsilyl)oxy]-1-cyclopentene-1-heptanoic Acid Methyl Ester 1-Cyclopentene-1-heptanoic acid, 5-oxo-3-[(triethylsilyl)oxy]-, Methyl ester, (R)- 1-Cyclopentene-1-heptanoic acid, 5-oxo-3-[(triethylsilyl)oxy]-, Methyl ester, (3R)- 1-Cyclopentene-1-heptanoic acid, 5-oxo-3-[(triethylsilyl)oxy]-, methyl ester, (3R)-
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CAS | 118456-54-5
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InChI | InChI=1/C19H34O4Si/c1-5-24(6-2,7-3)23-17-14-16(18(20)15-17)12-10-8-9-11-13-19(21)22-4/h14,17H,5-13,15H2,1-4H3/t17-/m0/s1 |
methyl 7-{(3R)-5-oxo-3-[(triethylsilyl)oxy]cyclopent-1-en-1-yl}heptanoate - Physico-chemical Properties
Molecular Formula | C19H34O4Si
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Molar Mass | 354.56 |
Density | 0.99±0.1 g/cm3(Predicted) |
Boling Point | 413.2±45.0 °C(Predicted) |
Flash Point | 169.262°C |
Solubility | Dichloromethane |
Vapor Presure | 0mmHg at 25°C |
Appearance | Oil |
Color | Colourless |
Storage Condition | 2-8°C |
Refractive Index | 1.471 |
methyl 7-{(3R)-5-oxo-3-[(triethylsilyl)oxy]cyclopent-1-en-1-yl}heptanoate - Introduction
Methyl (3R)-5-oxo-3-[(triethylsilyl) oxy]-1-cyclopentene-1-heptanoate is an organic compound commonly known by the abbreviation TMS methyl ester. The following is a brief description of its nature, use, preparation and safety information:
Nature:
Methyl (3R)-5-oxo-3-[(triethylsilyl) oxy]-1-cyclopentene-1-heptanoate is a colorless liquid with an odor. It is a flammable substance and is soluble in organic solvents such as ethanol and methylene chloride.
Use:
TMS methyl ester is mainly used as a protecting group reagent in organic synthesis reactions. It is capable of protecting the alcohol and acid functional groups to prevent undesired side reactions during the reaction. At the same time, TMS methyl ester can also be used as a volatile standard in mass spectrometry analysis.
Preparation Method:
The preparation of TMS methyl ester is usually obtained by reacting methyl formate with triethylsilylphenol under appropriate conditions. The specific reaction conditions can be optimized and adjusted according to actual needs.
Safety Information:
TMS methyl ester is a flammable liquid, and care should be taken to avoid fire and high temperatures. It is irritating to the eyes, skin and respiratory tract, so wear personal protective equipment such as protective glasses, gloves and gas masks during use. When used in a closed environment, it is necessary to ensure good ventilation conditions. In the event of contact with the substance, the affected area should be flushed immediately with water and treated promptly with medical attention. When storing and handling this compound, the relevant safety procedures should be strictly observed.
Last Update:2024-04-09 21:11:58